If you’ve hit peri or post-menopause and your body suddenly feels like it’s working against you, you’re not alone — and you’re not imagining it.
A drop in estrogen creates three major hormonal changes that directly affect your metabolism and make weight loss feel harder than it used to.
The good news?
Once you understand these changes, you can work with your body again. I know this because I’ve lived through it myself… for a painstaking 8 years and counting!
Let’s break down the three biggest hormone pathways affected by menopause — and why they matter for your weight, energy, and overall health.
Estrogen normally helps regulate cortisol, your body’s primary stress hormone.
Once estrogen drops:
Cortisol tends to run higher
Stress responses become stronger
The HPA axis (hypothalamus-pituitary-adrenal axis) controls your stress response.
Estrogen normally helps modulate this system, keeping cortisol spikes moderate.
When estrogen drops, the HPA axis can overreact to minor stressors, sending more cortisol into your bloodstream than before.
Sleep becomes lighter or more disrupted
And higher cortisol has consequences — it promotes fat storage, especially around the midsection. It also increases cravings and raises blood sugar, which can make weight loss feel frustratingly slow.
Even if your thyroid labs are “normal,” reduced estrogen makes your thyroid hormones less effective. This can lead to:
A slower metabolism
Lower energy
Increased fatigue
Easier weight gain
Women often say, “I’m eating the same but gaining weight.” Or worse yet, “I’m 100% sticking to my moderate calorie-deficit diet and nothing is happening!” (that was me 👋 … many times).
This is exactly what you’d expect when thyroid activity becomes less efficient.
It’s important to look at all thyroid lab results AND symptoms combined, not just TSH as many doctors do.
This is the big one.
Estrogen plays a major role in how sensitive your body is to insulin — the hormone that moves sugar into your cells.
When blood sugar or insulin levels are elevated, your body interprets it as a signal to store energy rather than burn it.
This “storage mode” promotes fat accumulation, particularly around the abdomen, and makes weight loss more difficult.
I recently experimented with a continuous glucose monitor for a two week period and was shocked at what I discovered – despite my squeaky clean diet!
These hormonal shifts — higher cortisol, reduced thyroid efficiency, and lower insulin sensitivity — all add up to:
Slower metabolism
More hunger and cravings
Increased fat storage
Difficulty losing weight with methods that used to work
This isn’t a mindset issue.
It’s not a motivation issue.
And it’s definitely not a willpower issue.
It’s physiology.
Even though estrogen declines naturally, the downstream effects aren’t fixed.
They can respond to the right habits — especially those that improve insulin sensitivity, support thyroid function, and regulate cortisol.
Some of the most effective strategies include:
Eating enough protein (aim for 1 gram per pound of goal body weight)
Building muscle through strength training (muscle increases resting metabolic rate)
Managing stress and improving sleep (to reduce cortisol levels in the body)
Moving strategically throughout the day (especially after eating to help improve insulin efficiency)
Choosing meals that stabilize blood sugar (protein forward, with lots of veggies)
Improving insulin sensitivity by supplementing with Berberine
Omitting alcohol –
it disrupts all three of these key metabolic pathways; it spikes cortisol, worsening stress-driven fat storage; impairs insulin sensitivity, leading to higher blood sugar and fat accumulation; and can interfere with thyroid hormone production and conversion, slowing metabolism
These aren’t quick fixes — they’re metabolic tools.
And they work. Trust me. I’ve experimented and have years of data to share!
If your body feels different in peri-menopause or post-menopause, it’s because it is different. Understanding what’s happening inside your metabolism is the first step toward taking back control — and creating real, lasting results.
If you’d like help applying these strategies or want to learn more about how I coach women through these changes, get in touch! I’m always here to support you 😊
The entire contents of this website are based upon the opinions of Build Holistic Nutrition. Please note that Build Nutrition is not a dietitian, physician, pharmacist or other licensed healthcare professional. The information on this website is NOT intended as medical advice, nor is it intended to replace the care of a qualified health care professional. This content is not intended to diagnose or treat any diseases. Always consult with your primary care physician or licensed healthcare provider for all diagnosis and treatment of any diseases or conditions, for medications or medical advice, as well as before changing your health care regimen.
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